TOPICAL PROTEASE INHIBITOR INCREASES TUMOR-FREE AND OVERALL SURVIVAL IN CD4-DEPLETED MOUSE MODEL OF ANAL CANCER

Topical Protease Inhibitor Increases Tumor-Free and Overall Survival in CD4-Depleted Mouse Model of Anal Cancer

Patients with immunodeficiencies and older age are at an increased risk of anal cancer.Transgenic K14E6/E7 mice with established high-grade anal dysplasia were treated topically at the anus with the protease inhibitor saquinavir (SQV) in the setting of CD4+ T-cell depletion white chocolate digestives to mimic immunodeficiency.To ensure tumor develo

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Study on Development of Double Heterogeneous Subgroup Parameters

Since the Fukushima nuclear accident, the safety of nuclear fuel under accident conditions has been paid more and more attention.As an accident-tolerant fuel, coated particle fuel has become a research hotspot.In this fuel element, a large number of fuel particles are dispersed in non-fissile matrix materials.The National Oak Ridge Laboratory of th

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Knowledge Source Rankings for Semi-Supervised Topic Modeling

Recent work suggests knowledge sources can be added sten jacket m into the topic modeling process to label topics and improve topic discovery.The knowledge sources typically consist of a collection of human-constructed articles, each describing a topic (article-topic) for an entire domain.However, these semisupervised topic models assume a corpus t

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